A Second Case
Lithium used in the treatment of bipolar disorder.
-
- renal toxicity
- impaired urinary concentrating ability
- natriuresis,
- renal tubular acidosis,
- tubulointerstitial nephritis
progressing to chronic kidney disease and hypercalcemia.
most common adverse effect is
nephrogenic diabetes insipidus, (20-40% of patients within weeks of initiation of Rx.
Lithium nephropathy is uncommon ,occurring in 15% s(3)
Radiology
- innumerable micro cysts randomly distributed in BOTH
- cortex and medulla or predominantly cortex are
- usually 1-2 mm in diameter.
- Cysts arise from distal tubular structures and collecting ducts.
- Best seen on T2W MRI images.